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Litesizer™ 500 Particle Analyzer

Litesizer™ 500 Particle Analyzer
Litesizer™ 500 Particle Analyzer
Product Code : 01
Product Description

Particle analysis at the touch of a button

The Litesizer™500 is an instrument for characterizing nano- and microparticles in dispersions and solutions. It determines particle size, zeta potential, and molecular mass by measuring dynamic light scattering (DLS), electrophoretic light scattering (ELS), and static light scattering (SLS).

A highlight of the Litesizer™ 500 is its ingeniously simple software. We have created a one-page workflow, where input parameters, results and analysis are all on a single page: You can set up your experiments in a few seconds, and produce the analyses and reports you need at the touch of a button.

Key Features

cmPALS - new patented technology for zeta potential

With cmPALS (European Patent 2 735 870), measurements can be performed at much lower applied electric fields, and within significantly shorter measuring times, thereby enabling reliable measurements of even highly sensitive samples.

Unique Ω-shaped capillary tube for zeta potential

Measurements are more stable and reproducible because of the unique Ω-shaped capillary in the cuvette.

Particle-size measurements: Unprecedented resolution

Several different particle sizes in a single suspension can be precisely resolved, thanks to highly developed algorithms in the firmware.

Continuous transmittance measured automatically

Transmittance gives you instant feedback about your sample, and allows automatic optimization of measurement parameters (angle, focus position, and measurement duration).

Ingeniously simple software, Kalliope™

Kalliope™ provides an intuitive one-page workflow, where input parameters, measurements and analyses are all at hand. Kalliope™ is fully compliant with the FDA's 21 CFR part 11 FDA regulations.

Technical Specifications :

General specifications

Temp. control range

0-90 oC

Light source

Laser / 40 mW, 658 nm

Laser warm-up time

6 min

Ambient operating temp.

10-35 oC

Humidity

up to 90 % non-condensing

Dimensions (W, D, H)

460 mm, 485 mm, 135 mm

Weight

approx. 18 kg (40 lb)

Particle size specifications

Measuring range

0.3 nm - 10 μm (particle diameter)

Sensitivity

min. conc. (protein)

0.1 mg/mL (lysozyme)

min. conc. (polymer)

1 µg/mL (polystyrene latex)

Accuracy

Better than +/-2 % on certified reference material

Repeatability

Better than +/-2 % on certified reference material

Minimum sample volume

20 µL

Measurement angles

15o, 90o, 175o

Zeta potential specifications

Measuring range

-600 to +600 mV

Mobility

10-11 m²/V.s to 2 x 10-7 m²/V.s

Size range

3.8 nm - 100 µm

Sensitivity

1 mg/mL (lysozyme)

Maximum sample concentration

40 % w/v

Sample volume

350 µL

Maximum sample conductivity

200 mS/cm

Molecular mass specifications

Measuring range (mass)

980 Da - 20 MDa

Measuring range (particle size)

up to 40 nm (diameter)

Sensitivity

0.1 mg/mL (lysozyme)

Accuracy

+/-10 %

Repeatability

+/-5 %

Measurement angle

90o

Transmittance specifications

Size range

No limit

Measuring time

10 s

Minimum sample volume

20 µL


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